Saturday, December 5, 2015

materialsscienceandengineering: Surface roughness puts off...



materialsscienceandengineering:

Surface roughness puts off bacteria

A simple process that roughens the surface and alters the grain size of metallic biomedical implants could deter the bacteria that cause infections and complications after surgery, according to researchers from Politecnico di Milano, Massachusetts Institute of Technology, Northeastern University, University of Cambridge, and King Abdulaziz University [S. Bagherifard et al., Biomaterials (2015), DOI: 10.1016/j.biomaterials.2015.09.019].

Stainless steel is widely used for medical devices and weight-bearing bone implants where its surface roughness and grain structure are known to have a profound effect on cell function. In fact, mechanical cues like these can have a greater effect than chemical ones on bacterial adhesion and the formation of undesirable bacterial colonies known as biofilms.

“The growing resistance of bacteria to conventional antibiotics, the need to develop advanced orthopedic implants with improved biocompatibility, along with the necessity of using a mechanically strong material able to withstand physiological strains and stresses, gave us the impetus for the development of advanced materials for bone implants,” explains Sara Bagherifard of Politecnico di Milano.

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This.

This is huge.



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